

CDC: Put Your Medicines Up and Away and Out of Sight.Lock it Up: Medicine Safety in Your Home.Health care professionals, patients, and consumers can sign up for email alerts about Drug Safety Communications on medicines or medical specialties of interest to you. We urge health care professionals and consumers to report side effects involving diphenhydramine and other medicines to the FDA MedWatch program, using the information in the “Contact FDA” box at the bottom of the page. It is also available in combination with pain relievers, fever reducers, and decongestants. Diphenhydramine is marketed under the brand-name Benadryl, store brands, and generics. When used as recommended, it is a safe and effective medicine. It works by blocking histamine in the body, which is a substance that causes allergic symptoms. In the event of an overdose, health care professionals should attempt to determine whether a patient with a suspected overdose took diphenhydramine.ĭiphenhydramine is an antihistamine used to temporarily relieve symptoms due to hay fever, upper respiratory allergies, or the common cold, such as runny nose and sneezing. Encourage teens and caregivers to read and follow the Drug Facts label. Health care professionals should be aware that the “Benadryl Challenge” is occurring among teens and alert their caregivers about it. If someone takes too much diphenhydramine and is hallucinating, can’t be awakened, has a seizure, has trouble breathing, or has collapsed, immediately get medical attention or contact poison control at 1-80 or online. Do not take more than the dose listed on the label, as doing so can cause serious problems. FDA recommends you lock up medicines to prevent accidental poisonings by children and misuse by teens, especially when they are home more often due to the COVID-19 pandemic and may be more likely to experiment.Īlways read the Drug Facts label included on all OTC medicines to find out if they contain diphenhydramine, how much and how often you should take them, and important safety information. We also contacted TikTok and strongly urged them to remove the videos from their platform and to be vigilant to remove additional videos that may be posted.Ĭonsumers, parents, and caregivers should store diphenhydramine and all other OTC and prescription medicines up and away and out of children’s reach and sight.
Benadryl hallucination challenge update#
We will update the public once we have completed our review or have more information to share. We are investigating these reports and conducting a review to determine if additional cases have been reported. We are aware of news reports of teenagers ending up in emergency rooms or dying after participating in the “Benadryl Challenge” encouraged in videos posted on the social media application TikTok. Food and Drug Administration (FDA) is warning that taking higher than recommended doses of the common over-the-counter (OTC) allergy medicine diphenhydramine (Benadryl) can lead to serious heart problems, seizures, coma, or even death. Drug Safety Communication (PDF - 59KB) 09-24-2020 FDA Drug Safety Communication
